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W2 Neurobiology - Diversity of GABAergic Inhibitory Synapses in the Healthy and Diseased Brain

Prof. Dilja Krüger-Burg – Institute of Anatomy, University Medical Center Mainz
With assistance from the ReALity initiative, Prof. Dilja Krüger-Burg was appointed to the Institute of Anatomy, UMC. She investigates the diversity of GABAergic inhibitory synapse in health and disease and was awarded a Heisenberg Professorship. Prof. Krüger-Burg’s research particularly contributes to the ReALity focus areas on linking molecules to cells and organisms, through identification of the effects of individual GABAergic synaptic protein components on neuronal network function and behavioral outcomes, and linking animal models with patients, through assessment of effects of patient mutations on specific GABAergic complexes. In particular, the focus on anxiety and stress-related disorders will explore plasticity of the GABAergic postsynaptic machinery as a resilience mechanism and will contribute to the understanding of its role in ageing.