Bioinformatics of Nanopore Technology
Third generation long-read sequencing technologies, such as Nanopore sequencing (Nano-seq), provide unprecedented opportunities to solve many complex biomedical problems. They have the potential to, once again, revolutionize the field of sequencing similarly to the rise of the Next-Generation-Sequencing (NGS)-technology during the last two decades. Critical for unleashing the full potential of long-read sequencing is the concerted co-development of experimental and computational techniques. The establishment of this technology at JGU and UMC has a pioneering character for several fields of application. It seamlessly integrates with nearly all core features of the ReALity initiative (vital computational and bioinformatics aspects, molecular mechanisms, technological advances) and bridges between UMC and JGU in a truly multidisciplinary way.