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Co-Translational Quality Control in Eukaryotic Cells

Jun.-Prof. Marie-Luise Winz – Institute of Pharmaceutical and Biomedical Sciences, JGU
RNA modifications are linked to a variety of health problems and are often associated to age-related dysfunctions including, but not limited to, neurogenerative diseases. Jun.-Prof. Winz, who was recently recruited to Mainz, has long-standing expertise in the field of RNA research with a focus on co-translational quality control. Collaborative projects within several research initiatives in Mainz are already planned or established. The equipment for gradient centrifugation, fractionation, and UV crosslinking funded by ReALity will be the basis for establishing polysome isolation techniques in Mainz. This will foster the above-mentioned interactions with RNA research groups and play a key role for interdisciplinary research at the center of ReALity research areas.