Molecular Principles that Regulate Gene Expression by Liquid-Liquid Phase Separation
Dr. Lukas Stelzl – Institute of Molecular Physiology, JGU/Institute of Molecular Biology
ReALity recruited Dr. Stelzl to the JGU as a junior group leader with associate group leader status at the IMB. He is biochemist by training and his research focuses on how liquid-liquid phase separation of disordered proteins and nucleic acids regulates cellular processes and how this affects longevity and ageing using innovative multi-scale simulations and data science, including artificial intelligence. With his expertise, he bridges a deep understanding of biophysical experiments (NMR, single-molecule FRET, EPR and SAXS) and multi-scale simulations, a strong background in biology and the ability to design and implement novel algorithms. Together with collaboration partners at JGU/IMB and within the Rhine-Main University consortium, he will push forward biochemical research on cellular regulation by phase-separation and Cell Biology 2.0, thereby enriching the core units of ReALity and the Institute for Quantitative Biomedicine.
